Trusted by NHS organisations, healthcare providers, and healthtech innovators, 6B delivers full-lifecycle CLEO EPS integration, from discovery and architecture through development, testing, deployment, and ongoing support. We build secure, scalable integrations for outpatient prescribing, patient demographics, clinical context, medicines workflows, operational reporting, and patient engagement.
Our team combines medicines management knowledge with expertise in healthcare APIs, HL7 FHIR, NHS Spine services, dm+d terminology, identity management, event-driven integration, and clinical safety. We support established prescribing workflows while protecting data integrity, maintaining auditability, and enabling safe electronic prescription exchange.
Understanding CLEO EPS
CLEO EPS is an electronic prescribing solution designed to enable clinicians to create prescriptions digitally and send them electronically to a community pharmacy chosen by the patient. The platform achieved NHS Digital accreditation in 2022.
The solution is used across secondary care outpatient, community, urgent care, and other prescribing environments where organisations want to replace paper-based prescription processes with electronic workflows.
CLEO EPS uses FHIR messaging standards and supports electronic prescription exchange through NHS EPS infrastructure. CLEO also supports local or bespoke formularies and prescribing data for reporting and operational insight.
Depending on the deployment, CLEO EPS may operate alongside EPR, PAS, clinical record, pharmacy, and other digital healthcare systems, allowing prescribing workflows to fit into wider patient journeys.
Our CLEO EPS Integration Process
We begin with structured discovery involving clinical, pharmacy, digital, technical, operational, and governance stakeholders. Together, we define prescribing workflows, users, data requirements, safety constraints, and intended outcomes.
Typical integrations include patient demographics, encounter information, prescriber context, medication information, allergies, clinical records, prescribing workflows, formulary data, prescription status, and operational analytics.
We map patient identifiers, encounters, prescriber details, medication identifiers, dose instructions, routes, frequencies, quantities, prescription items, nominations, prescription statuses, cancellations, and dispensing-related information.
Architecture may use FHIR APIs, REST APIs, NHS Spine services, integration engines, secure web services, database interfaces, or event-driven messaging. We also define mappings for dm+d, local formularies, dose units, routes, frequencies, prescription statuses, and prescribing instructions.
Authentication can support NHS identity services, single sign-on, OAuth 2.0, OpenID Connect, service accounts, and role-based access according to the target environment.
Reusable components accelerate delivery, including FHIR components, medication handlers, authentication flows, validation rules, transformation frameworks, and routing pipelines. Secure testing validates patient matching, medication coding, prescriber permissions, prescription content, sequencing, cancellations, acknowledgements, audit trails, failure recovery, and reconciliation.
Before launch, we coordinate acceptance testing, clinical safety review, deployment, and documentation. After go-live, we monitor integrations, resolve issues, and maintain compatibility with CLEO EPS, NHS EPS services, and connected systems.
Benefits of CLEO EPS Integration
Prescribers gain access to connected patient and medication information while creating electronic prescriptions, reducing reliance on disconnected systems and paper processes.
Pharmacy teams benefit from prescriptions being transmitted electronically through EPS, supporting clearer and more efficient prescribing-to-dispensing workflows. NHS EPS allows prescriptions to be sent electronically to the dispenser selected by the patient.
Patients benefit from being able to have eligible prescriptions sent electronically to a convenient community pharmacy rather than relying on a paper prescription.
Digital and operational teams gain improved visibility of prescribing activity, prescription status, service usage, and workflow performance.
Healthcare providers can connect outpatient, community, and urgent care prescribing more effectively with wider digital patient pathways.
For healthtech vendors, CLEO EPS integration provides standards-based access to established NHS electronic prescribing workflows.
Why Choose 6B for CLEO EPS Integration?
6B designs around the complete prescribing journey, keeping patient, prescriber, medication, and prescription information accurate, traceable, and clinically meaningful.
Our specialists understand HL7 FHIR, APIs, NHS Spine services, OAuth 2.0, OpenID Connect, integration engines, secure web services, and event-driven messaging.
We manage complex medicines terminology, including dm+d, formularies, dose units, routes, frequencies, prescription statuses, medication identifiers, and system mappings.
Reusable medication handlers, authentication flows, transformation frameworks, validation tools, connectors, and monitoring components accelerate delivery without compromising quality.
Security, governance, and clinical safety are embedded through encryption, role-based access, audit logging, data minimisation, retention controls, and sensitive-information safeguards.
Estimate the Cost of Your CLEO EPS Integration Project
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Want to speak to someone today? Call 6B on 0113 350 1290.
Readiness checklist for CLEO EPS Integration
- Define the prescribing workflows and use cases your integration will support, such as outpatient prescribing, community prescribing, urgent care, prescription tracking, cancellations, or analytics.
- Identify the CLEO EPS, EPR, PAS, clinical record, pharmacy, patient-facing, and third-party systems involved in each workflow.
- Confirm which FHIR APIs, NHS Spine services, integration-engine connections, REST APIs, database interfaces, or secure transfer methods are available within the target deployment.
- Define which system will act as the source of truth for each data type and how corrections, duplicate records, conflicting updates, rejected messages, and reconciliation will be managed.
- Confirm authentication, authorisation, NHS identity, single sign-on, role-based access, encryption, service-account, and audit-logging requirements.
- Prepare governance and clinical safety documentation, including your lawful basis, DPIA, DSPT position, and applicable DCB0129 or DCB0160 responsibilities.
Speak To Our CLEO EPS Integration Experts
Whether you're developing a new digital health product or extending an existing solution with CLEO EPS integration, 6B brings the technical expertise, healthcare insight, and experience needed to accelerate delivery.
